Assessing TRIV202 To Reverse Subvalular Aortic Stenosis (SAS) In Dogs
OPEN FOR RECRUITMENT
TriviumVet is supplying TRIV202 to the Morris Animal Foundation research into subvalvular aortic stenosis (SAS), the most common congenital heart defect in dogs. The purpose of this study is to evaluate whether three-times weekly dosing with oral rapamycin (TRIV202) can reverse the heart muscle changes associated with SAS in dogs. As the current treatment options are limited in this disease, this has the potential to provide further treatment options to improve quantity and quality of life for dogs affected by this disease.
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We are excited to support UC Davis and the Morris Animal Foundation in a novel research. Subvalvular aortic stenosis (SAS) is a common heart defect in dogs which often leads to sudden death. The clinical trial will investigate whether rapamycin can reduce the life-threatening heart remodelling...